Users of this Web site should not rely on information provided on this Web site for their own health problems. View abstract. Intern Med J. A., Attele, A. S., Zhang, L., and Yuan, C. S. Anti-HIV activity of medicinal herbs: usage and potential development. Ong, E. S., Len, S. M., and Lee, A. C. Differential protein expression of the inhibitory effects of a standardized extract from Scutellariae radix in liver cancer cell lines using liquid chromatography and tandem mass spectrometry. Hu, J. 11-1-2009;284(2):198-207. How It Works Purported Uses and Benefits Do Not Take If Side Effects Special Point Back to top For Maternal and Child Health Care of China 2011;26(10):1529-1531. View abstract. View abstract. Morgan SL, Baggott JE, Moreland L, et al. Polysaccharides inhibit proliferation and downregulate phospho-c-Met expression and downstream phospho-Erk/Akt signaling(18). Song, S. J., Li, F. F., Xu, Y., Zhang, L. H., Yuan, F., and Zhang, Y. Phytochemistry 2011;72(8):752-760. View abstract. Yotsumoto, H., Yanagita, T., Yamamoto, K., Ogawa, Y., Cha, J. Y., and Mori, Y. Inhibitory effects of oren-gedoku-to and its components on cholesteryl ester synthesis in cultured human hepatocyte HepG2 cells: evidence from the cultured HepG2 cells and in vitro assay of ACAT. If combined with such drugs, it can have potential side effects, as resulted in a laboratory test. Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death. View abstract. J Interferon Cytokine Res 2008;28(9):571-581. It is not an approved drug. Toxicology 3-4-2009;257(1-2):80-85. It can cause drowsiness, fever, lung inflammation, and other information-related issues. Levy RM, Khokhlov A, Kopenkin S, et al. Li T.T, Xu H.M, and Liang Z.W. There could be several possible side effects of Scutellaria baicalensis if taken by mouth. FDA Alerts Consumers About Potentially Life-Threatening Health Problems Linked to Limbrel. Kim M, Lee BC. Baicalin is believed to interfere with hormonal reactions and release of histamines and bile in the body; it stimulates gallbladder activity, inhibits inflammation, as well as suppresses the activity of leukaemia-derived T-cells and replication of viruses and bacteria. Certain flavonoid components appear to have anticancer activity in vitro: wogonin caused G1 arrest, while baicalin and baicalein cause G2/M accumulation(2). It is also effective against some bacteria. If you take it, consider monitoring your blood sugar level regularly and pay proper attention to the amount of Baikal skullcap. Lixuan, Z., Jingcheng, D., Wenqin, Y., Jianhua, H., Baojun, L., and Xiaotao, F. Baicalin attenuates inflammation by inhibiting NF-kappaB activation in cigarette smoke induced inflammatory models. Planta Med 2001;67(5):396-399. Li BQ, Fu T, Gong WH, et al. Int J Oncol. 2nd ed. View abstract. Hui KM, Wang XH, Xue H. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site. A preliminary study of S. baicalensis along with metformin appeared to improved glucose tolerance, inflammation, and gut microbiota in patients with type 2 diabetes(23). J Neurochem. Lu, H. F., Hsueh, S. C., Ho, Y. T., Kao, M. C., Yang, J. S., Chiu, T. H., Huamg, S. Y., Lin, C. C., and Chung, J. G. ROS mediates baicalin-induced apoptosis in human promyelocytic leukemia HL-60 cells through the expression of the Gadd153 and mitochondrial-dependent pathway. Daugel'-Dauge, N. O., Durnev, A. D., Kulakova, A. V., Seredenin, S. B., and Velichkovskii, B. T. [Corpuscular mutagenesis and its prevention]. View abstract. Pharmacology 2006;77(2):71-77. Chem Pharm Bull (Tokyo) 1992;40(2):531-533. Med Hypotheses. This beneficial medicinal herb has many uses to treat different diseases and health conditions. View abstract. Shin NR, Gu N, Choi HS, Kim H. Combined effects of Scutellaria baicalensis with metformin on glucose tolerance of patients with type 2 diabetes via gut microbiota modulation. Monitor your blood sugar closely. View abstract. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. View abstract. Food Chem Toxicol. View abstract. A Scutellaria Baicalensis Root Extract trade name mixture (30% ethanol extract) is reported to contain flavonoid compounds. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. View abstract. Dygai, A. M., Suslov, N. I., Skurikhin, E. G., Churin, A. Lee BH, Lee SJ, Kang TH, et al. Jiang, R. H., Su, W. C., Liu, H. F., Huang, H. S., and Chao, J. I. Jeong, K., Shin, Y. C., Park, S., Park, J. S., Kim, N., Um, J. Y., Go, H., Sun, S., Lee, S., Park, W., Choi, Y., Song, Y., Kim, G., Jeon, C., Park, J., Lee, K., Bang, O., and Ko, S. G. Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice. View abstract. View abstract. Biochem Biophys Res Commun 9-24-2000;276(2):534-538. View abstract. Ann N Y Acad Sci 2007;1095:521-526. Arch Dis Child 1993;68:468-71. The compound baicalein exhibited only inhibitory effects(9). J Ethnopharmacol. High temperature effects on flavones accumulation and antioxidant system in Scutellaria baicalensis Georgi cells. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. These include the Chinese Skullcap, Huang Qin, Scutellaria baicalensis (the scientific name), and the Hooded Willow Herb. J Ethnopharmacol. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. Zhang, K., Guo, Q. L., You, Q. D., Yang, Y., Zhang, H. W., Yang, L., Gu, H. Y., Qi, Q., Tan, Z., and Wang, X. Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. Cancer Lett. View abstract. J Ethnopharmacol. WebDescription:scutellaria baicalensis root extract is an extract of the roots of the scutellaria baicalensis, lamiaceae. Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. 2000;23(5):272-274. View abstract. Baikal skullcap might change how quickly the liver breaks down these medications. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. J Chromatogr.A 3-19-2010;1217(12):1875-1881. Eksp.Klin Farmakol. 1997;57(1):63-67. View abstract. Baikal skullcap might affect the thyroid and may affect how antithyroid medications work. J Chromatogr.B Analyt.Technol Biomed.Life Sci 4-15-2011;879(13-14):1023-1028. Scutellaria barbata has been studied for its anticancer properties, but more research is needed. J Ethnopharmacol 2005;98:295-300. In combination with other herbs, Baikal skullcap is used to treat attention deficit-hyperactivity disorder (ADHD), prostate cancer, a lung condition called bronchiolitis, arthritis, and hemorrhoids. J Altern Complement Med 2002;8(5):567-572. WebDescription:scutellaria baicalensis root extract is an extract of the roots of the scutellaria baicalensis, lamiaceae. View abstract. Yang, D., Hu, H., Huang, S., Chaumont, J. P., and Millet, J. Clin Pharmacol Ther 2007;82:726-33. View abstract. Scutellaria baicalensis | Memorial Sloan Kettering Cancer Scutellaria Macrantha , Scutellaria Baicalensis, Family: Lamiaceae. View abstract. View abstract. Talk with your healthcare provider before using this product if you are taking lithium. Therefore, if you are a diabetic patient, you should stay away from such herbs. However, different extraction methodologies and/or plant origins have yielded varying degrees of antitumor effects(21). Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo[a]pyrene 7,8-dihydrodiol and benzo[a]pyrene 7,8-dihydrodiol-9,10-epoxide. 2004;23(8):874-878. Details. J Ethnopharmacol. View abstract. B., Ro, J. Y., and Woo, S. S. Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. 1990;36(5):602-607. Mol Urol. Pharmacogenomics of human OATP transporters. 7-28-2004;211(1):39-46. S. barbata flavonoids have produced synergistic effects in combination with cisplatin in ovarian cancer cells(32). 2019;133:109402. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. Typical doses (see individual product information): Dried herb: 1 to 2 g 3 times/day; Tea: 240 mL 3 times/day (pour 250 mL of boiling water over 5 to 10 mL of the dried herb and steep for 10 to 15 minutes); Tincture: 2 to 4 mL 3 times/day. View abstract. J Ethnopharmacol. View abstract. View abstract. 5-17-2011;135(2):359-368. In animal models, attenuation of asthma was attributed to reduced airway injury and restored mitochondrial function(19). Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel View abstract. Effects of Mg-ATP on the flavonoid production in the Scutellaria baicalensis Georgii suspension cultures. WebScutellaria Baicalensis Extract. In this article, we explore the top Baicalin benefits that you can experience today. Clin Pharmacol Ther 2007;82:726-33. 2011;31(4):1130-1132. View abstract. View abstract. Antitumor activity of chloroform fraction of, In vitro anti-leukemic activity of the ethno-pharmacological plant. Kim, B. R., Kim, D. H., Park, R., Kwon, K. B., Ryu, D. G., Kim, Y. C., Kim, N. Y., Jeong, S., Kang, B. K., and Kim, K. S. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. Hao, H., Aixia, Y., Dan, L., Lei, F., Nancai, Y., and Wen, S. Baicalin suppresses expression of Chlamydia protease-like activity factor in Hep-2 cells infected by Chlamydia trachomatis. Liao, H. L. and Hu, M. K. Synthesis and anticancer activities of 5,6,7-trimethylbaicalein derivatives. Memorial Sloan Kettering does not record specific website user information and does not contact users of this website. View abstract. Eye contact Rinse with water. View abstract. Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. 1999;385-6, 400-1. Scheck, A. C., Perry, K., Hank, N. C., and Clark, W. D. Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells. View abstract. Diabetes medications are also used to lower blood sugar. View abstract. Biological properties of baicalein in cardiovascular system. Ye F, Wang H, Jiang S, et al. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. Li L, Gao H, Lou K, et al. 9-7-2009;125(2):286-290. CAS #:94279-99-9 | EC #:304-845-9. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others. May Help Fight Cancer Cells. Enomoto, R., Koshiba, C., Suzuki, C., and Lee, E. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. , we explore the top Baicalin benefits that you can experience today medicinal plants used! And other information-related issues in this article, we explore the top Baicalin benefits that you can experience.... S., Son, E. J., kim, M., Nam,.... Effects, as resulted in a laboratory test product if you are taking lithium barbata! And anticancer activities of Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism benzo! The top Baicalin benefits that you can experience today this article, explore! 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